| 1. | Which of the following statements concerning multiple sclerosis is INCORRECT? |
| A. | Genetic susceptibility and environmental factors are involved in this pathogenesis. |
| B. | The demyelinating disease is initiated by an immune-mediated inflammatory process. |
| C. | The typical age of onset is between 20-40 years, with the highest prevalence in young men. |
| D. | Most patients have an initial relapsing remitting course. |
| E. | 20% of patients have progressive course of disease from onset. |
| 2. | All of the following statements regarding disease modifying therapies(DMTs) in multiple sclerosis is correct EXCEPT: |
| A. | Beta-interferon can reduce relapse frequency by 30-35%. |
| B. | Natalizumab is a first line DMTs for its being more effective than others. |
| C. | Fingolimod may cause first dose bradycardia and atrioventricular conductive block. |
| D. | Risk of teratogenicity is a serious concern for women who take teriflunomide. |
| E. | Risk of teratogenicity is a serious concern for women who take teriflunomide. |
| 3. | Which of the following statements concerning multiple sclerosis is CORRECT? |
| A. | Visual and cerebellum features are pathognomonic of MS. |
| B. | There is no specific diagnostic biomarkers available for MS. |
| C. | Magnetic resonance imaging (MRI) is an important diagnostic tool for MS. |
| D. | Dysphagia with dysphonia could be one of the signs of MS. |
| E. | Cerebrospinal fluid (CSF) analysis and visual evoked potentials are used as confirmatory tests for diagnosis of MS. |
| 4. | Ms. X is found to have a blood lead level (BLL) of 9µg/dL, which of the following options of management is advisable? |
| A. | This level is normal and no action is necessary. |
| B. | Education on low lead dietary intake and environmental avoidance of excessive lead exposure. |
| C. | Strict removal from lead exposure. |
| D. | Chelation therapy is usually indicated. |
| E. | Termination of pregnancy is justified for Ms. X. |
| 5. | Which one of the following statements best describes the adverse outcomes of chronic low to moderate levels of lead exposure? |
| A. | It causes hypertension. |
| B. | It causes renal impairment. |
| C. | It causes cognitive dysfunction. |
| D. | It causes adverse reproductive outcome. |
| E. | All of the above. |
| 6. | Which of the following statements concerning Lead exposure is CORRECT? |
| A. | Since the overall geometric mean blood Lead level has dropped dramatically, the risk from long term lead poisoning is no longer a concern. |
| B. | Lead persists for long periods in our body, with a half-life of 40 days in blood. |
| C. | The main way Lead is absorbed is through the gut and skin exposure. |
| D. | There are no legislation and regulation on the amount of Lead found in paints. |
| E. | Soaking and washing vegetables can only reduce Lead concentrations only slightly. |